How does the human mind innovate and create using past and present knowledge? What enhances--or impairs--our ability to optimally take advantage of our acquired experience and learning? How can we best promote mental agility to creatively and adaptively meet challenges and to make the most of opportunities across the lifespan? What cognitive, behavioral, and brain mechanisms are central to an agile mind? My lab, using the diverse and convergent methodologies of cognitive neuroscience, explores these questions focusing particularly on the role of different levels of specificity of mental representation and varying levels of cognitive control.