Matt Mc Gue

Photo of Matt Mc Gue

Contact Me

N-218 Elt H

75 E River Rd


I am a behavioral geneticist with two primary areas of research focus. The first concerns the development of substance use disorders from adolescence to adulthood. The second concerns genetic contributions to normative aging processes and mortality. My research on substance use disorders is based primarily on a series of long-term longitudinal studies I co-direct at the Minnesota center for Twin and Family Research at the University of Minnesota. My research on aging is primarily based in Denmark, where a hold a guest professor position in the Department of Epidemiology at the University of Southern Denmark. The links below provide brief descriptions of these projects.

Minnesota Twin Family Study (MTFS)

Sibling Interaction and Behavior Study (SIBS) and Research on Adoption

Danish Studies on Aging

Educational Background & Specialties

Educational Background

  • Ph.D.: University of Minnesota, Minneapolis, MN, 1981.

Curriculum Vitae


  • behavior genetics
  • individual differences
  • quantitative psychology
  • psychological aspects of aging
  • adolescent development
  • twin studies
  • substance abuse
Courses Taught
  • Psy 5137 - Introduction to Behavioral Genetics
  • Psy 8935 - Readings in Individual Differences and Behavioral Genetics
  • Psy 5993 - Seminar in Twin Family Research
  • Psy 1001 - Individual Differences Component in Team Taught Course
Research & Professional Activities

Professional Activities

  • President, Behavior Genetics Association: 2000 - 2003
  • Member, National Institute on Alcohol Abuse and Alcoholism National Advisory Council:
  • Chair, Department of Psychology, University of Minnesota: 1999 - 2001
  • Guest Professor, Department of Epidemiology, University of Southern Denmark :
  • President, International Society for Twin Research:
  • McGue, M., Osler, M., & Christensen, K. (2010). Causal inference and observational research: The utility of twins. Perspectives on Psychological Science, 5(5), 546-556. Download
  • Hicks, B. M., Durbin, C. E., Blonigen, D. M., Iacono, W. G., & McGue, M. (2012). Relationship between personality change and the onset and course of alcohol dependence in young adulthood. Addiction, 107(3), 540-548. Download
  • Vrieze, S. I., Hicks, B. M., Iacono, W. G., & McGue, M. (2012). Decline in Genetic Influence on the Co-Occurrence of Alcohol, Marijuana, and Nicotine Dependence Symptoms From Age 14 to 29. American Journal of Psychiatry, 169(10), 1073-1081. Download
  • Irons, D. E., Iacono, W. G., Oetting, W. S., & McGue, M. (2012). Developmental Trajectory and Environmental Moderation of the Effect of ALDH2 Polymorphism on Alcohol Use. Alcoholism-Clinical and Experimental Research, 36(11), 1882-1891. Download
  • McGue, M., & Christensen, K. (2013). Growing old but not growing apart: Twin similarity in the latter half of the lifespan. Behavior Genetics, 43(1), 1-12. Download
  • McGue, M., Keyes, M., Sharma, A., Elkins, I., Legrand, L., Johnson, W. & Iacono, W.G. (2007). The environments of adopted and non-adopted youth: Evidence on range restriction from the Sibling Interaction and Behavior Study (SIBS). Behavior Genetics, 37(3): 449-462. Download
  • McGue, M., Zhang, Y. W., Miller, M. B., Basu, S., Vrieze, S., Hicks, B., . . . Iacono, W. G. (2013). A Genome-Wide Association Study of Behavioral Disinhibition. Behavior Genetics, 43(5), 363-373. Download
  • McGue, M., & Irons, D. E. (2013). Etiology. In B. S. McCrady & E. S. Epstein (Eds.), Addictions: A comprehensive guidebook (pp. 36-72). New York: Oxford.
  • McGue, M., Skytthe, A., & Christensen, K. (2014). The nature of behavioural correlates of healthy ageing: a twin study of lifestyle in mid to late life. International Journal of Epidemiology, 43(3), 775-782. Download
  • Scholar of the College, College of Liberal Arts, University of Minnesota, 1998 - 2001
  • National Institute of Health Grants
  • Regents' Professor. University of Minnesota Board of Regents, 2007
  • Dobzhansky Award for Lifetime Contributions to Behavioral Genetic Research, 2011
  • Shields Award for Lifetime Contributions to Twin Research, 2007